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Animal Models Core

Core Training & Consultation

Stroke Surgery

Surgical-related equipment includes a rodent stereotax, Zeiss OPMI VISU surgery microscope, stereotaxic drills, ultraviolet curing light, and fiber optic illuminator. For tissue processing, there are two shared computer-interfaced stereological work-stations, which include two stereo light microscopes with high-resolution digital cameras and fluorescent capabilities, Leica VT1000S vibratome, and a benchtop microscope.

Brain Stimulation

Epidural Stimulation: The cortical stimulation protocol is run off of one PC laptop with custom software that can run up to five wireless stimulator boxes, each box connecting to one implanted electrode via radio frequency. The stimulation software allows each stimulator box to be set individually for exact frequency, current level, plus width, etc.

Behavioral Assessments

We have approximately 300 square feet of a dedicated room for behavioral assessment and training of rats. Dr. Adkins has all the necessary behavioral testing equipment for this research. For rats, there are four reaching chambers, two ladder tasks, two testing cylinders, video tracking EthoVision software, and a high-speed digital video camera suitable for frame- by-frame analyses of digital videos. For mice, she has enriched environment equipment and cage, a high- speed digital camera, two reaching chambers, two pasta and two single-pellet reaching platforms, two cylinder tasks, and two ladder tasks. Additionally, AAALAC approved animal housing rooms are available in the MUSC Childrens’ Research Institute.