The overarching goal of the MUSC DDRC Clinical Component is to create a research support infrastructure of biostatisticians and research operations team members to promote efficiencies in the design, implementation and analysis of research studies of therapies to improve clinical outcomes for patients with digestive diseases. MUSC has remarkable expertise in this area through the leadership of Valerie Durkalski-Mauldin, Ph.D., whose research specifically in digestive disease has been extraordinary. She and the other leaders of the Clinical Component specifically collaborate with DDRC members to receive statistical expertise and study operations in the planning of clinical as well as basic science research studies.
The DDRC Clinical Component leverages the expertise of the MUSC Data Coordination Unit (DCU) in the Department of Public Health Science. This entire group has an extensive record of collaborative research in digestive and liver disease. Importantly, the DCU has unparalleled statistical expertise for all phases of clinical and translational research. The DCU has developed and maintains an integrated web-based information system, WebDCU™, that combines the functions of Electronic Data Capture (EDC) and MUSC’s Clinical Trials Management System (CTMS). The team promotes an environment of collaboration, where they work closely with their partners on the design, planning and conduct of research.