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Rare lung disease tissue

Rare Lung Disease and COPD Research Group

Lymphangioleiomyomatosis (LAM) Research

Lymphangioleiomyomatosis (LAM) is a rare, progressive and systemic disease that typically results in cystic lung destruction. It predominantly affects women, especially during childbearing years. Here at MUSC we are currently running two LAM studies:

MIDAS: Safety and Durability of Sirolimus for Treatment of LAM

LAMP-1: LAM Pilot Study With Imatinib Mesylate

COPD Research

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that causes obstructed airflow from the lungs. Symptoms include breathing difficulty, cough, mucus (sputum) production and wheezing. We run a combination of weight loss in COPD, HIV in COPD, and Bronchoscopic Lung Volume Reduction studies (BLVR). We have two studies currently enrolling:

HOPE: HIV-associated Obstructive Pulmonary Disease and Emphysema

INSIGHT: INtervention Study In overweiGHT patients with COPD

Alpha-1 Antitrypsin Deficiency Research

Alpha-1 Antitrypsin Deficiency is a genetic disorder that may result in lung disease and/or liver disease. Complications may include COPD, cirrhosis, neonatal jaundice, or panniculitis. A1AD is due to a mutation in the SERPINA1 gene that results in not enough alpha-1 antitrypsin (A1AT). Here at MUSC we run the Alpha-1 Coded Testing (ACT) program, which is a free and confidential way to test for Alpha-1 Antitrypsin Deficiency. MUSC also houses the Alpha-1 Research Registry. The registry allows patients to enroll and stay up to date with current research in the field. The Alpha-1 Research page, which includes all of the current research studies being done.

Alpha-1 & LAM Current Team Members

Director: Charlton B. Strange, M.D., Professor

Co-Investigator: Tatsiana Beiko, M.D., Assistant Professor

Lab Manager: Danielle Woodford
woodfordd@musc.edu
843-792-6280

COPD Current Team Members

Director: Charlton B. Strange, M.D., Professor

Co-Investigator: Nicholas J. Pastics, Jr., M.D., Associate Professor

Co-Investigator: Tatsiana Beiko, M.D., Assistant Professor

Lab Manager: Danielle Woodford
woodfordd@musc.edu
843-792-6280

Study Coordination Staff:

Gwen Blanton
Program Coordinator
blantonm@musc.edu
843-792-8483

Whitney Billingsley
Program Coordinator I
lanewh@musc.edu
843-792-5556

Summer Blair
Student Research Assistant
blairsu@musc.edu

Kim Foil
Genetic Counselor
brownkl@musc.edu
843-792-6474 

Brooke Patton
Student Research Assistant
pattonb@musc.edu

Laura Schwarz
Research Coordinator
schwarzl@musc.edu
843-792-0260

Eryn Varano
Program Coordinator
varanoe@musc.edu
843-792-2121