access intranet after hours circle-arrow apply blog caret circle arrow close closer look community outreach community outreach contact contact us down arrow facebook lock solid find a provider find a clinical trial find a provider find a researcher find faculty find-a-service how to apply join leadership left arrow locations logo make a gift map location maximize minimize my chart my chart notification hp notification lp next chevron right nxt prev pay your bill play previous quality and safety refer a patient request a speaker request appointment request an appointment residents corner rss search search jobs Asset 65 submit a story idea symptom checker Arrow Circle Up twitter youtube Dino Logo External Link University Logo Color University Logo Solid Health Logo Solid Arrow Right Circle Book Calendar Date Calendar Search Date Diploma Certificate Dollar Circle Donate Envelope Graduation Cap Map Pin Map Search Phone Pills Podcast

Developmental Neurogenetics

Pediatrics

Training Programs

The Division of Developmental Neurogenetics is a research-based division that investigates normal brain development, neurodegenerative disorders and translational research for neuroprotective and neuroregenerative therapeutics.  They collaborate with clinicians who are interested in stroke and brain injury, including neonatal neurotprotection.  The scientists are also interested in disease mechanisms of birth defect disorders, perinatal insults, cerebral palsy and inherited disorders. As part of this program, researchers are examining the functional roles of sphingolipids in the development of childhood diseases such as neurodegenerative disorders, childhood cancers, vascular diseases and diabetes.The group uses several clinical rodent models related to the following diseases and students and postdoctoral fellows are trained in the following preclinical studies:

Childhood leukodystrophies caused by metabolic gene defect

  1. Adrenoleukodystrophy Disease
  2. Krabbe Disease

Acute brain injury

  1. Cerebral hypoxia and cerebral palsy
  2. Stroke and ischemia
  3. Spinal cord injury
  4. Traumatic brain injury

Chronic neuroinflammatory diseases

  1. Alzheimer disease and dementia
  2. Multiple sclerosis

Research Programs

View all research programs

Our Faculty

Contact Us

Division of Developmental Neurogenetics
Darby Children’s Research Institute
173 Ashley Avenue, CRI 509
MSC 515
Charleston, SC 29425
Phone: 843-792-3545
Fax: 843-792-3653