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COBRE Members

Principal Investigator

Kenneth D. Tew, Ph.D., DSc
Chair & Professor
Cell and Molecular Pharmacology and Experimental Therapeutics
John C. West Chair in Cancer Research

Investigators

Peggi Angel, Ph.D.
Assistant Professor
Cell and Molecular Pharmacology and Experimental Therapeutics
Systems-based analysis of redox activity in aortic valve stenosis

Seok-hyung Kim, Ph.D.
Assistant Professor
College of Medicine
Mitochondrial Disease Associated Mutations as novel Genetic Risk Factors to Develop Advanced Fatty Liver Disease

Gavin Wang, M.D., Ph.D.
Assistant Professor
Pathology and Laboratory Medicine
Targeting Cancer Stem Cells for Breast Cancer Treatment

Haizhen Wang, Ph.D.
Assistant Professor
Cell and Molecular Pharmacology and Experimental Therapeutics
Targeting CDK6 for T-cell acute lymphoblastic leukemia (T-ALL) therapy

Mentors

Richard R. Drake, Jr., Ph.D.
Professor
Cell and Molecular Pharmacology and Experimental Therapeutics

Scott T. Eblen, Ph.D.
Associate Professor
Cell and Molecular Pharmacology and Experimental Therapeutics

Anand Mehta, DPhil
Professor
Cell and Molecular Pharmacology and Experimental Therapeutics

Kenneth D. Tew, Ph.D., DSc
Chair & Professor
Cell and Molecular Pharmacology and Experimental Therapeutics
John C. West Chair in Cancer Research

Danyelle Townsend, Ph.D.
Associate Professor
Drug Discovery and Biomedical Sciences

Graduates

Sherine Chan, Ph.D.
Associate Professor
Drug Discovery and Biomedical Sciences

James Chou, Ph.D.
Associate Professor
Drug Discovery and Biomedical Sciences
Awarded RO1: Novel lysine deacetylase 6 Hsp domain inhibitors against AML (1R01CA163452-01A1)

Eduardo Maldonado, DVM, Ph.D.
Assistant Professor
Drug Discovery and Biomedical Sciences
Awarded RO1: VDAC Opening Small Molecules to Revert Warburg Metabolism and Induce Oxidative Stress

Mariana Pehar, Ph.D.
Assistant Professor
Cell and Molecular Pharmacology and Experimental Therapeutics
Awarded R01: NGF and RAGE-p75NTR signaling in models of amyotrophic lateral sclerosis

Danyelle Townsend, Ph.D.
Associate Professor
Drug Discovery and Biomedical Sciences

Joachim Uys, Ph.D.
Assistant Professor
Cell and Molecular Pharmacology and Experimental Therapeutics
Awarded R01: GSTP-Mediated Redox Protein Signaling and Binge-line Ethanol Drinking

Marcelo Vargas, Ph.D.
Assistant Professor
Cell and Molecular Pharmacology and Experimental Therapeutics
Awarded RO1: NAD metabolism and mitochondrial dysfunction in ALS models (R01NS089640)

COBRE Internal Advisory Board

Kathleen T. Brady, M.D., Ph.D.
Distinguished University Professor
Associate Dean for Clinical Research

Alan Diehl, Ph.D.
Professor of Biochemistry and Molecular Biology
Endowed Chair Lipidomics & Pathology

Phil Howe, Ph.D.
Professor
Biochemistry and Molecular Biology
Endowed Chair for Clinical Oncology

Keith Kirkwood, D.D.S., Ph.D.
Professor
Associate Dean of Research
College of Dental Medicine

Igor Roninson, Ph.D.
Professor
SCCP Pharmaceutical and Biomedical Sciences -USC Campus

COBRE External Advisory Board

Kenneth D. Tew, Ph.D., DSc
Medical University of South Carolina

Franklin G. Berger, Ph.D.
University of South Carolina

Yvonne Janssen-Heininger, Ph.D.
The University of Vermont

Dean P. Jones, Ph.D.
Emory University of Medicine

Garth Powis, D. Phil
Sanford Burnham Prebys Medical Discovery Institute

Peter J. van Bladeren, Ph.D.
Nestlé: Retired Vice President of Regulatory & Scientific Affairs