With so many impactful findings coming out of the College of Medicine, we are delighted to showcase some of the more significant research publications. On a periodic basis, COM leadership selects papers to highlight from nominations for publications that have appeared in high impact journals with an MUSC faculty member as first or last author.
John Wrangle, MD, MPH (on right), Assistant Professor of Medicine - Hematology/Oncology, and Mark Rubinstein, PhD (left), Assistant Professor of Surgery, were recognized for their work and article, “ALT-803,an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer; a non-randomized, open-label, phase 1btrial”, published in The Lancet Oncology, May, 2018 (Volume 19 – Issue 5).
Jeffrey Korte, PhD, Associate Professor of Epidemiology and Public Health Sciences, was recognized for his work and article, "Impact of HIV Self-Test Distribution to Male Partners of ANC Clients: Results of a Randomized Controlled Trial in Kenya”, published in the Journal of Acquired Immune Deficiency Syndrome, December 1, 2018 (Volume 79 - Issue 4).
Dr. Christopher Cowan and Dr. Makoto Taniguchi were highlighted for their work and article titled “HDAC5 and Its Target Gene, Npas4, Function in the Nucleus Accumbens to Regulate Cocaine-Conditioned Behaviors” published in Neuron, September 27, 2017.
Dr. Donald R. Menick and Dr. Lillianne H. Wright were recognized for their work and article titled “Angiokine Wisp-1 is increased in myocardial infarction and regulates cardiac endothelial signaling” published in JCI Insight, February 22, 2018.
Dr. Donna Roberts, Associate Professor of Radiology and Radiological Science, was highlighted for her work and article titled “Effects of Spaceflight onAstronaut Brain Structure as Indicated on MRI” published in the New England Journal of Medicine, Volume 377, No. 18, November 2, 2017.
Dr. ShikharMehrotra, Associate Professor in the Department of Surgery, was recognized for his work and article titled “CD38-NAD+AxisRegulates Immunotherapeutic Anti- Tumor T Cell Response” published in Cell Metabolism, Volume 27, Issue 1, January 2018.
Dr. Stephen A. Duncan, SmartState and Department Chair in the Department of Regenerative Medicine, was highlighted for his work and article titled “A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia” published in Cell Stem Cell, Volume 20, Issue 4.
Dr. Philip H. Howe, Hans and Helen Koebig Chair in Clinical Oncology and Chair of the Department of Biochemistry and Molecular Biology, was recognized for his work and article titled “Cathepsin-B-mediated cleavage of Disabled-2 regulates TGF-_-induced autophagy” published in Nature Cell Biology, Volume 18, Number 8.
Dr. Zihai Li (pictured on right), Chair and Professor in the Department of Microbiology & Immunology, was highlighted for his work and article titled “Platelets subvert T cell immunity against cancer via GARP-TGFᵦ axis” published in the May 2017 issue of Science Immunology.
Dr. Shaun Olsen, Assistant Professor in the Department of Biochemistry and Molecular Biology, was highlighted for his work and article titled “S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity” published in the February 16, 2017, issue of Molecular Cell.
Dr. Betty Tsao was highlighted for her work and article, "A missense variant in NDF1 is associated with susceptibility to multiple autoimmune diseases," published in the January 30, 2017, issue of Nature Genetics.
Dr. Luttrell was given the award for his work and article, "The conformational signature of arestin3 predicts its trafficking and signaling functions," published in the March 31, 2016, issue of Nature.