Patrick A. Flume, M.D., is the Powers-Huggins Endowed Chair for Cystic Fibrosis Professor. Flume’s work is focused on patients with cystic fibrosis (CF), bronchiectasis, and non-tuberculous mycobacteria (NTM) lung infections. These patients have multiple challenges including management of their chronic infection and consequences of the treatment. We have multi-disciplinary teams engaged in the care of these patients and so our investigations also include quality improvement, mental health, toxicities of medications, best practices for treatment of infections and exacerbations.
He is recognized by the national and international CF community having served on the CF Foundation Center Committee, the Adult Care Consensus Committee, and the Advisory Task Force on Adult Issues, the Professional Education Committee, the European CF Society's Best Practices committee, and as founding co-chair of the CF Foundation's Pulmonary Practice Guidelines Committee. He co-led the International Working Group on Antimicrobial Resistance in Cystic Fibrosis. He is the editor-in-chief for the Journal of Cystic Fibrosis.
He serves as associate vice president for Clinical Research, leads a clinical research program for CF, bronchiectasis, and NTM, and is co-PI for the South Carolina Clinical & Translational Research Institute. Many of these studies are related to new drug and therapy development for patients, but he also has an interest in determining optimal management of CF pulmonary exacerbations and is the co-PI in the STOP trials, aimed at identifying optimal treatments for exacerbations.
Senior Author PubMed Collection (senior author publications are most often associated with mentored projects)