access intranet after hours circle-arrow apply blog caret circle arrow close closer look community outreach community outreach contact contact us down arrow facebook lock solid find a provider find a clinical trial find a provider find a researcher find faculty find-a-service how to apply join leadership left arrow locations logo make a gift map location maximize minimize my chart my chart notification hp notification lp next chevron right nxt prev pay your bill play previous quality and safety refer a patient request a speaker request appointment request an appointment residents corner rss search search jobs Asset 65 submit a story idea symptom checker Arrow Circle Up twitter youtube Dino Logo External Link University Logo Color University Logo Solid Health Logo Solid Arrow Right Circle Book Calendar Date Calendar Search Date Diploma Certificate Dollar Circle Donate Envelope Graduation Cap Map Pin Map Search Phone Pills Podcast

Specialized Center of Research Excellence

Specialized Center of Research Excellence (SCORE) on Sex Differences

The past decade has seen an impressive increase in research in the area of women’s health due, in large part, to the efforts of NIH through the Office of Research in Women’s Health (ORWH). In September 2018, the National Institute on Drug Abuse and the Office of Research on Women’s Health renewed a 5-year award for Drs. Aimee McRae-Clark and Kathleen T. Brady, funding a research center focused on sex and gender-based multidisciplinary research at MUSC. The Medical University of South Carolina’s (MUSC) Specialized Center of Research Excellence (SCORE) on Sex and Gender Factors Affecting Women’s Health is one of six specialized centers in the United States charged with the task of advancing research on women’s health and promoting institutional interdisciplinary research.

The MUSC SCORE is a productive interdisciplinary research center focused on sex and gender differences as they uniquely relate to addiction and stress-related disorders. It serves as a focal point for women's health research at MUSC and is comprised of three core research components, a leadership administrative core, a career enhancement core, a biostatistics support core, and a Pilot Project Program. Our core scientific projects focus on sex and gender differences in the relationship between addiction and stress response using emerging technology in closely aligned clinical and basic science projects. The overarching goals of the center focus on supporting and improving the translational scientific collaborations of the core and pilot research projects, catalyzing further growth of interdisciplinary sex and gender-based research on the MUSC campus and creating strategic partnerships to enhance the translation and dissemination of SCORE findings and other relevant research to improve the health of women and girls.

Specific Aims

Specific Aim 1: Expand the well-established interdisciplinary translational program of research at MUSC focused on sex/gender differences in addictions and interactions of sex/gender, stress and addictions.

Specific Aim 2: Provide critical resources through the Leadership Administrative Core to assist investigators in increasing efficiency, maximizing scientific rigor and productivity, and collecting pilot data.

Specific Aim 3: Encourage and support the growth of interdisciplinary sex- and gender-based research on the MUSC campus and nationwide.

Specific Aim 4: Through the Career Enhancement Core, attract and mentor young investigators and new faculty in the area of sex- and gender-based research.

Specific Aim 5: Develop strategic partnerships for the purpose of increasing research productivity and enhancing the dissemination of research findings highlighting the importance of sex and gender influences in the optimization of therapeutic strategies.

Gender Differences on Health & Disease

Research on sex and gender differences — research that spans basic studies on cells to large, clinical trials involving thousands of patients — aims to understand health differences between males and females at all levels. The knowledge will improve health for both women and men.

More facts about how sex and gender influences health and disease

Application Information

There are currently calls for applications for MUSC’s Specialized Center of Research Excellence (SCORE) Career Enhancement Core (CEC) Scholar Program and Pilot Project Program.

For full RFAs and application instructions, read the SCORE 2019 RFAs (PDF).

Please direct questions to SCORE Coordinator Amanda Wagner at wagne@musc.edu.

SCORE CEC Scholar Program

The purpose of this Career Enhancement Core is to provide salary support and research funds to promising junior faculty and senior fellows/post-doctoral trainees pending faculty appointment with a doctorate and less than 5 years of research training at MUSC to collect initial data for an R03, R21, or R01 submission. The project must focus on sex and gender differences as they uniquely relate to stress-related disorders. The project can be either clinical or basic science, and projects involving multidisciplinary teams and/or translational research efforts are especially encouraged.

Online applications are due by March 1, 2019 at 5 p.m. (EST) 

Interested candidates who plan on applying should provide a Letter of Intent to the SCORE Coordinator (wagne@musc.edu) no later than January 7, 2019.

SCORE Pilot Project Program

The purpose of the Pilot Program is to provide short-term start-up funds to promising postdoctoral fellows and junior faculty (less than 5 years from post-doctoral training/terminal degree) at MUSC to collect initial data for an R03, R21, or R01 submission. The project must focus on a neuroscience-related topic and explore either sex/gender differences or disorders/treatments as they uniquely relate to women. The project can be either clinical or basic science, and projects involving multidisciplinary teams and/or translational research efforts are especially encouraged.

Applications will be accepted via email to the SCORE Coordinator (wagne@musc.edu) between the dates of December 15, 2018 and February 1, 2019.