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Mike Yost PhDOur research mission is to create a bedside to bench and back again culture of discovery and innovation at MUSC.  We are translating the latest developments, understanding and technology into improved surgical patient care resulting in shorter stays, enhanced post-operative quality of life and reduced overall healthcare cost to both patients and stakeholders.

I invite you to learn more about our exciting research in Cardiovascular, Surgical Oncology, Transplant & Immunology and Regenerative Medicine research. 

Michael J. Yost, Ph.D. FAIMBE
Professor of Surgery and Bioengineering
Vice Chairman for Research, Department of Surgery

 Our Laboratories

Cardiovascular Research

The Cardiovascular Surgery Research Lab uses an integrative bedside-to-bench-to-bedside approach to translational research, exploring many aspects of cardiothoracic and vascular diseases but perhaps none more so than our research in aortic aneurysm disease.

Surgical Oncology Research

The surgeon-scientists and basic researchers in the Surgical Oncology Research Laboratory, under the leadership of Nancy DeMore, M.D.  and Shikhar Mehrotra, Ph.D., are conducting research to understand T cell biology and develop enhanced T cell-based therapeutics for the treatment of cancer. 

Transplant Immunobiology Research

Organ transplantation has become an accepted modality for the treatment of end-stage organ failure, but chronic rejection remains a leading cause of graft loss. The Lee Patterson Allen Transplant Immunobiology Lab is dedicated to the study of novel investigations in transplantation tolerance. 

Regenerative Medicine Research

Research in regenerative medicine explores ways to create living, functional tissues to repair or replace tissue or organ function lost due to age, disease, damage, or congenital defects.

Transplant Surgery Research

Dave Taber, PharmD, BCPS, and John McGillicuddy, M.D. in the Divsion of Transplant Surgery collaborate on research to improve medication safety for transplant patients.

Our Services

Center for Cellular Therapy

The Center for Cellular Therapy (CCT) is an FDA registered cGMP level facility that meets the most rigorous standards in the aspect of processing of cells.

Clinical Trials

The surgeon-scientists and basic researchers in Department of Surgery are an integral part of many of the large number of clinical trials that MUSC participates in.