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Biography
Dr Bharioke did his undergraduate degree at the University of Toronto, graduating with a double major in Biochemistry and Chemical Physics (focusing on theoretical quantum mechanics) and a minor in Mathematics. With an interest in understanding how brains perform computations, he did his PhD under Mitya Chklovskii and Simon Laughlin, jointly between the University of Cambridge and HHMI's Janelia Research Campus. He worked on identifying theoretically-driven structure-function relationships in the Drosophila visual connectome. For his postdoctoral work, he transitioned to working in the more complex circuitry of the mouse cortex, working with Botond Roska in Basel, Switzerland. He focused on understanding how cortical circuits change their activity both during early development, and during the cognitive state changes associated with the loss of consciousness. To answer these questions, he learned to perform two-photon imaging and also developed a novel method to record form embryonic mouse neurons, in vivo. Now, in Charleston, his lab will be combining optical methods to interrogate circuits with computational modelling and simulations, to build a holistic understanding of how cortical circuits form, respond to changes, and generate cognitive functions.