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Daria Ilatovskaya Ph.D.

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Rank
  • Assistant Professor
College
  • College of Medicine
Department
  • Medicine
Academic Focus
  • water and electrolyte homeostasis
  • regulation of renal ion channel function
  • cardiorenal diseases
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Biography

Dr. Daria Ilatovskaya moved to the Division of Nephrology at MUSC as an Assistant Professor in December 2017 from the Medical College of Wisconsin (Department of Physiology), where she had pursued her postdoctoral training and early faculty years under mentorship of Prof. Alexander Staruschenko. Dr. Ilatovskaya studies the role of electrolyte transport in control of cardiorenal function and blood pressure, which is a highly clinically relevant problem. The number of people living with hypertension is predicted to be 1.56 billion worldwide by the year 2025. In the US alone in 2011-2012, about a third of all people over the age of 20 were diagnosed with high blood pressure and took medications to help control it. CDC reported that total costs associated with high blood pressure in 2011 in the US were $46 billion. Dr. Ilatovskaya’s research is aimed at advancing our understanding of the mechanisms that underlie kidney disease and facilitating faster translation of the science knowledge into clinics.

Specifically, Dr. Ilatovskaya’s laboratory is investigating the regulation of ion channels and transporters in the hormonal aspect of salt-sensitive hypertension and polycystic kidney disease. The lab uses both in vivo and in vitro techniques to investigate these phenomena using an integrative approach that includes studies on the molecular, cellular and whole organism levels.  In addition to routine molecular biology techniques, the lab specializes in unique methods, such as single-channel electrophysiology on freshly isolated nephron segments, state-of-the-art confocal and epifluorescence microscopy, chronic blood pressure monitoring and other sophisticated techniques.

The lab currently has a postdoctoral fellow, Dr. Iuliia Polina, and a research technician Mark Domondon, BSc. We are actively training summer students and looking forward to having one more postdoctoral fellow, Dr. Pavel Vlasov, join the lab in fall.