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Lori McMahon PhD

Lori Lynn McMahon PhD

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843-792-4333

mcmahonl@musc.edu

173 Ashley Avenue Room Suite 105

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Rank
  • Professor
College
  • College of Medicine
Department
  • Neuroscience
Academic Focus
  • Synaptic Physiology
  • neurodegenerative disease and neuropsychiatric illness, with a focus on synaptic plasticity and sex differences
  • investigation of mechanisms that modulate synaptic function and plasticity at hippocampal synapses in rodent models
Faculty email addresses should not be used to seek medical advice or to make medical appointments. Please visit MyChart for medical appointments or to contact your provider.

Locations

Office Location
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room

Biography

Dr. McMahon joined the Medical University of South Carolina in 2021 as Professor of Neuroscience and served as the Vice President for Research through May 2024. She has been investigating various mechanisms that modulate synaptic function and plasticity at hippocampal synapses in rodent models over the lifespan in health and disease for 20 years. She is an expert synaptic physiologist and her lab uses electrophysiological approaches in acute brain slices, including extracellular dendritic field potential recordings, population spike recordings, and whole-cell voltage and current clamp recordings, to measure cell excitability, synaptic transmission and plasticity. She has experience investigating synaptic transmission in all hippocampal subfields, many areas of cortex, and dorsal striatum. Her lab also has extensive expertise in protein measurement using Western blot, immunohistochemical staining and confocal imaging, hippocampal behavioral assays, stereotaxic surgery for drug administration, to complement the synaptic physiology.