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Gavin Wang MD, PhD

Gavin Yong Wang MD, PhD

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  • Assistant Professor
  • College of Medicine
  • Pathology and Laboratory Medicine
Academic Focus
  • Cellular Senescence
  • Neuroscience/Neurodegenerative Diseases
  • Developmental Cancer Therapeutics
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MD: Chongqing Medical University 
PhD: Peking Union Medical College  
Post-Doctoral Fellow: Medical University of South Carolina  


Cellular Senescence
Neurodegenerative Disorders 
Developmental Cancer Therapeutics

Academic Biography:  

 Dr. Gavin Wang is a tenure-track faculty member of the Department of Pathology and Laboratory Medicine at the Medical University of South Carolina (MUSC) and a full member of the developmental cancer therapeutics (DCT) program of Hollings Cancer Center.  He is a physician-scientist with extensive research experience in the areas of cellular senescence, stem cell biology, oxidative stress and redox signaling, cancer cell biology, experimental therapeutics, and neuroscience.  Dr. Wang is among the pioneers whose studies have demonstrated that the induction of senescence is a prominent response of a variety of tissue-specific stem cells as well as many types of tumor cells to irradiation and various anti-cancer therapies.  A number of recent studies, including those from the Wang lab, have linked aging-associated accumulation of senescent cells in the brain to the pathogenesis and progression of Alzheimer’s disease (AD).  On the basis of these results, Dr. Wang’s lab recently has launched an exciting new project aimed at defining the mechanisms by which senescent glial cells affect the onset, progression, and treatment of AD.  Moreover, his lab has recently embarked on a new research program studying how lipid metabolic reprogramming in cancer cells contributes to tumor progression and cancer disparities.  Dr. Wang has served as the leading Principle Investigator (PI) or project PI on several NIH-funded projects and has published more than 45 peer-reviewed research articles, invited reviews and book chapters.  He is a full member of the American Association for Cancer Research (AACR) and the Radiation Research Society (RRS).  He also has considerable experience with grant review and has served as a reviewer for various funding agencies including NIH, DOD and NASA.  In addition, Dr. Wang has reviewed a multitude of manuscripts for many scientific journals including Cancer Research, Oxidative Medicine and Cellular Longevity, Cell Death and Disease, Molecular Therapy, and Biochemical Pharmacology.