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Tim Barnoud PhD

Thibaut Barnoud PhD

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Rank
  • Assistant Professor
College
  • College of Medicine
Department
  • Biochemistry and Molecular Biology
Academic Focus
  • The role of p53 variants in cancer risk
  • Personalized medicine approaches based on p53 status
  • Targeting heat shock proteins for the treatment of cancer
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Locations

Office Location
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Biography

 

Education and Training:  

 

2016-2021 Postdoctoral Fellow, Molecular and Cellular Oncogenesis Program, The Wistar Institute

 

2010-2015  Ph.D., Department of Biochemistry and Molecular Genetics, University of Louisville

 

2005-2009 B.A., Department of Biology, University of Louisville

 

Research:

 

Dr. Barnoud’s laboratory uses genetically engineered mouse models (GEMMs) to study the p53 tumor suppressor, the most frequently mutated gene in human cancer. The main goal of the Barnoud Lab is to study the impact of p53 variants on cancer risk and response to therapy.  A second major research focus is to understand the role of heat shock proteins (HSPs) on the initiation and progression of cancer.  The Barnoud Lab employs a series of inhibitors that target HSPs with the hopes of developing effective cancer therapies, with a focus on gastrointestinal (GI) cancers.