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Gavin Wang MD, PhD

Gavin Yong Wang MD, PhD

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  • Associate Professor
  • College of Medicine
  • Pathology and Laboratory Medicine
Academic Focus
  • Cellular Senescence/Stem Cell Biology
  • Neuroscience/Neurodegenerative Diseases
  • Developmental Therapeutics
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MD: Chongqing Medical University 
PhD: Peking Union Medical College  
Post-Doctoral Fellow: Medical University of South Carolina  


Cellular Senescence
Neurodegenerative Disorders 
Developmental Cancer Therapeutics

Academic Biography:  

 Dr. Gavin Wang is a tenure-track faculty member of the Department of Pathology and Laboratory Medicine at the Medical University of South Carolina (MUSC) and a full member of the developmental cancer therapeutics (DCT) program of Hollings Cancer Center.  He is a physician-scientist with extensive research experience in the areas of cellular senescence, stem cell biology, oxidative stress and redox signaling, cancer cell biology, experimental therapeutics, and neuroscience.  Dr. Wang is among the pioneers whose studies have demonstrated that the induction of senescence is a prominent response of various types of cells, including cancer stem cells (CSCs) and glial cells in the brain, to irradiation and various anti-cancer therapies.  Several recent studies, including those from Dr. Wang's lab, have linked aging-associated accumulation of senescent cells in the brain to the pathogenesis and progression of Alzheimer’s disease (AD).  On the basis of these results, Dr. Wang’s lab recently has launched an exciting new study aimed at defining the mechanisms by which senescent glial cells affect the onset, progression, and treatment of AD.  Moreover, his lab has recently embarked on a new research program studying how lipid metabolic reprogramming in cancer cells contributes to tumor progression and cancer disparities.  Dr. Wang has served as the leading Principle Investigator (PI) or project PI on several NIH-funded projects and has published more than 50 peer-reviewed research articles, invited reviews and book chapters.  He is a full member of the American Association for Cancer Research (AACR), Radiation Research Society (RRS), and Society for Neuroscience (SfN).  He also has considerable experience with grant review and has served as a reviewer for various funding agencies including NIH, DOD and NASA.  In addition, Dr. Wang has reviewed a multitude of manuscripts for many scientific journals including Cancer Research, Oxidative Medicine and Cellular Longevity, Free Radical Biology and Medicine, Cell Death and Disease, Molecular Therapy, and Biochemical Pharmacology.