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Jen Wang PhD

Haizhen Wang PhD

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  • Assistant Professor
  • College of Medicine
  • Cell and Molecular Pharmacology and Experimental Therapeutics
Academic Focus
  • Cancer Biology
  • Cancer Metabolism
  • Cancer Immunology
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Dr. Wang received her Ph.D. from the Georgia State University. She then pursued postdoctoral study with Dr. Peter Sicinski at the Dana-Farber Cancer Institute, Harvard Medical University. Dr. Wang was then recruited to the NCI-Designated Hollings Cancer Center at MUSC and established her independent research program in the Department of Cell and Molecular Pharmacology and Experimental Therapeutics at Medical University of South Carolina in 2018. The focus of Dr. Wang’s laboratory is to understand the mechanisms of tumor progression through analysis of both the cancer cells as well as the tumor infiltrated immune cells.

Selected Publications:

1,Haizhen Wang, Brandon N. Nicolay, Joel M. Chick, Xueliang Gao, Yan Geng, Hong Ren, Hui Gao, Guizhi Yang, Juliet A. Williams, Jan M. Suski, Mark A. Keibler, Ewa Sicinska, Ulrike Gerdemann, W. Nicholas Haining, Thomas M. Roberts, Kornelia Polyak, Steven P. Gygi, Nicholas J. Dyson & Piotr Sicinski. The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival. Nature. 2017, 546: 426-430.

2, Jinfang Zhang*, Xia Bu*, Haizhen Wang*, Yasheng Zhu, Yan Geng, Naoe Taira Nihira, Yuyong Tan, Yanpeng Ci, Fei Wu, Xiangpeng Dai, Jianping Guo, Yuhan Huang, Caoqi Fan, Shancheng Ren, Yinghao Sun, Gordon J.Freeman#, Piotr Sicinski#, Wenyi Wei#. Cyclin D/CDK4 kinase destabilizes PD-L1 via Cullin 3 SPOP to control cancer immune surveillance. Nature 2018, 553: 91–95. (*These authors contributed equally.)